(+)-Costunolide，CAS
553-21-9

Catalogue Number
C697550

Chemical Name
(+)-Costunolide

Synonyms
Costunolide; [3aS-(3aR*,6E,10E,11aS*)]-3a,4,5,8,9,11a-Hexahydro-6,10-dimethyl-3-methylene-cyclodeca[b]furan-2(3H)-one; (E,E)-6α-Hydroxy-germacra-1(10),4,11(13)-trien-12-oic Acid γ-Lactone; Costunolid; Costus lactone; NSC 106404;

CAS Number
553-21-9

分子式：
C₁₅H₂₀O₂

Appearance
White to Off-White Solid

Melting Point
106 - 109ºC

Molecular Weight
232.32

Storage
-20°C

Solubility
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Category
Standards; Pharmaceutical/API Drug Impurities/Metabolites;

Applications
(+)-Costunolide is an inhibitor of osteoclast differentiation, acting as an anti-inflammatory and anti-oxidant agent. It is a sesquiterpene lactone which mediates apoptosis.

参考文献
Cheon, Y. et al.: Phytother. Res., 28, 586 (2014); Butturini, E. et al.: Eur. J. Pharm., 730, 107 (2014);