(+)-Coclaurine Hydrochloride，CAS
19894-19-0

Catalogue Number
C633555

Chemical Name
(+)-Coclaurine Hydrochloride

Synonyms
(R)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol Hydrochloride; 1βH-Coclaurine Hydrochloride; (1R)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol Hydrochloride (1:1)

CAS Number
19894-19-0

Alternate CAS #
free base: 2196-60-3

分子式：
C₁₇H₁₉NO₃•HCl

Molecular Weight
285.34 + (36.46)

Category
Standards; Pharmaceutical/API Drug Impurities/Metabolites;

Applications
(+)-Coclaurine Hydrochloride is a benzyltetrahydroisoquinoline alkaloid extracted from Magnolia salicifolia. (+)-Coclaurine Hydrochloride is the salt form of (+)-Coclaurine. (+)-Coclaurine is used in Chinese medicine to improve memory via IGF-1R activation.

参考文献
Watanabe, H., et al.: J. Pharmacobiodyn., 10, 793 (1983); Hung, I., et al.: J. Biomol. Struct. Dyn., (2013), 31(12), 1411-1439