
磷脂-聚乙二醇-羧基 自组装PEG脂质体 DSPE-PEG-COOH (Carboxylic acid functionalized PEG Lipid)
货号:RS-0000068
CAS:PEG: 25322-68-3
分子量:N/A
分子式:N/A
单位:瓶
纯度:98%
外观:固态粉末或颗粒
储存温度:冷藏密封避光
溶剂:N/A
基本信息
磷脂-聚乙二醇-羧基自组装PEG脂质体 DSPE-PEG-COOH
DSPE-PEG-COOH是一种自组装PEG脂质体,它结合了磷脂的疏水性和聚乙二醇的亲水性,并引入了羧基官能团。这种结构特性使其能在水溶液中自发形成脂质体,并通过羧基与含有氨基或其他反应基团的药物或生物分子进行偶联,实现药物的装载和靶向传递。因此,DSPE-PEG-COOH在药物传递、生物偶联和生物医学工程等领域具有潜在的应用价值。
Description:
DSPE-PEG-COOH is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a carboxylic acid. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a COOH group for conjugation with amine-containing molecules. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide.
磷脂-聚乙二醇-羧基自组装PEG脂质体 DSPE-PEG-COOH的基本信息:
中文名称:磷脂-聚乙二醇-羧基
英文简称:DSPE-PEG-COOH
英文全称:Carboxylic acid functionalized PEG Lipid
CAS号:n/a; PEG: 25322-68-3; DSPE: 1069-79-0
主链结构:二嵌段共聚物
亲疏水性:两亲性
产品类型:自组装PEG衍生物
外观/形态:固态粉末或颗粒(以实际外观为准)
磷脂-聚乙二醇-羧基自组装PEG脂质体 DSPE-PEG-COOH的结构式:
产地:西安
用途:科研
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